BACT/ALERT® 3D

Optimizing Collection to Care

The BACT/ALERT 3D instrument is a state-of-the-art, automated microbial detection system. The BACT/ALERT system offers advantages in every dimension of microbial detection testing.

From its space-saving modular design to its easy touch-screen operation and flexible data management options, every size laboratory can perform microbial detection with the BACT/ALERT 3D.

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Overview

Uses

BACT/ALERT 3D is used for detecting the presence or absence of microorganisms in:

Blood
Sterile body fluids

Features & Benefits

Because it's so easy to use, BACT/ALERT 3D saves time, facilitates cross-training and helps prevent errors. This system offers immediate bottle recognition, putting you in control of bottle loading and unloading and virtually eliminating bottle handling errors during microbial detection testing. The system's automatic, built-in quality control, along with a low false positive rate and a rapid response time of this system, means you do more in less time with greater accuracy.

The latest generation of BACT/ALERT Culture Media brings the most advanced, innovative microbial growth and detection technology to your laboratory. BACT/ALERT media provide unsurpassed performance, in the detection of a wide variety of microorganisms including bacteria, fungi, and yeasts.

With flexible data management options of an automated microbial detection system, and available with many different system options, BACT/ALERT 3D allows you to choose the best configuration for your laboratory.

Plastic Bottles Mean Safety
Safety is an important consideration for any microbial testing. bioMérieux is committed to providing the safest products possible to the microbiology laboratory. BACT/ALERT bottles are made of unbreakable plastic to protect them from breakage. They are also lightweight to reduce the cost of disposal and shipping.

Specs

BACT/ALERT 3D: Healthcare Features & Specs

Results are the most important aspect of any microbial detection system. Built on bioMérieux's patented colorimetric technology, the BACT/ALERT 3D demonstrates unsurpassed recovery of a wide range of organisms.

BACT/ALERT 3D System Options

We've designed a microbial detection system to meet your individual needs. The modular design of the BACT/ALERT 3D enables the most flexible, ergonomic configuration to meet space limitations. The control module manages all bottle inventory and data, while the incubator module performs the testing.

BACT/ALERT 3D Combination Module

The BACT/ALERT 3D Combination Module is an integrated system that uses only 20 inches of bench space. Now, even the smallest laboratories can get the highest-quality microbiology test results on-site.

Uses

BACT/ALERT 3D: Healthcare Uses

For Clinical Laboratory:

For Clinicians and Administrators:

Microbial detection
Sepsis and quality control testing
Monitoring for the presence or absence of microorganisms
Data management/integration
Instrumentation interfacing

Workload efficiency
OSHA guidelines
Patient/employee safety
Data management/integration
Cost savings

Fan Plus Media

Optimized Time to Detection and Microorganism Recovery

The next-generation Fastidious Antimicrobial Neutralization Plus media (FAN Plus) from bioMérieux features optimized time to detection and microorganism recovery with an improved environment that fosters microbial growth for bacteria and yeast. FAN® Plus media offers effective organism growth from both blood and sterile body fluid samples, along with growth performance guidelines for use in delayed entry conditions.

Fastidious Antimicrobial Neutralization Plus Media (FAN® Plus)

FAN Plus media with Adsorbent Polymeric Beads (APB) to neutralize antimicrobials

Bottle Type	Media Formulation	Specimen Type	Specimen Volume
BACT/ALERT FA Plus Ref: 410851	30 mL of supplemented complex media containing adsorbent polymeric beads	Blood or normally sterile body fluid (SBF)	Up to 10 mL
BACT/ALERT FN Plus Ref: 410852	40 mL of supplemented complex media containing adsorbent polymeric beads	Blood or SBF	Up to 10 mL
BACT/ALERT PF Plus Ref: 410853	30 mL of supplemented complex media containing adsorbent polymeric beads	Blood	Up to 4 mL

Additional Media & Supplies

Product	Description	Specimen Type	Specimen Volume
BACT/ALERT SA Standard Aerobic Ref: 259789	Polycarbonate plastic bottles to be used with BACT/ALERT Microbial Detection Systems in qualitative procedures for the recovery and detection of aerobic microorganisms (bacteria and fungi).	Blood or normally sterile body fluid (SBF)	Up to 10 mL
BACT/ALERT SN Standard Anaerobic Ref: 259790	Polycarbonate plastic bottles to be used with BACT/ALERT Microbial Detection Systems in qualitative procedures for the recovery and detection of anaerobic and facultative anaerobic microorganisms (bacteria).	Blood or normally sterile body fluid (SBF)	Up to 10 mL

Product

Description

Specimen Type

Specimen Volume

BACT/ALERT MUP Culture Bottle Ref: 419744
To be used with Ref: 414997

Polycarbonate plastic bottles to be used in conjunction with BACT/ALERT 3D Mycobacteria Detection Systems for recovery and detection of mycobacteria.

Digested or decontaminated clinical specimens and sterile body specimens other than blood

0.5 mL

BACT/ALERT Mycobacterial Antimicrobial Supplement (MAS) Kit

Ref: 414997

Lyophilized Antimicrobial supplement and Nutrient Supplement to be used with BACT/ALERT MP Culture Bottles

Product	Description	Specimen Type	Specimen Volume
BACT/ALERT BPA Aerobic Platelet Culture Bottles Ref: 423278	Polycarbonate plastic bottles to be used with BACT/ALERT Microbial Detection Systems in for quality control testing of platlets. BACT/ALERT BPA culture bottles support the growth of aerobic microorganisms (bacteria and fungi).	LRAP or LRWBPC	4 - 10 mL
BACT/ALERT BPN Anaerobic Platelet Culture Bottles Ref: 423279	Polycarbonate plastic bottles to be used with BACT/ALERT Microbial Detection Systems in for quality control testing of platlets. BACT/ALERT BPN culture bottles support the growth of anaerobic and facultative anaerobic microorganisms (bacteria).	LRAP or LRWBPC	4 - 10 mL

Product	Description	Packaging
ITL SampLok® Adapter Cap 3 Ref: A100760	Blood culture collection adapter that is smaller and lighter than similar products to make disposal easier and potentially more cost-efficient (female threaded luer).	600 per case
ITL SampLok® Adapter Cap 3 Insert Ref: A100761 To be used with Ref: A100760	Optional insert for use with vacuum tubes and long-neck culture bottles.	840 per case
VACUETTE® Blood Culture Holder Ref: 450181	Graduated neck design to accommodate evacuated tubes without the need for an insert (female threaded luer).	320 per case

Software

BACT/ALERT 3D: Healthcare Software

BACT/ALERT 3D Signature:

The BACT/ALERT 3D Signature is a powerful microbiology workstation with comprehensive capabilities. It is ideal for higher-volume laboratories, university settings, or where expanded flexibility in operating routines, reporting and data management are needed.

BACT/ALERT 3D Select:

The ideal choice for routine microbial testing in areas where expanded data management or laboratory information system (LIS) connectivity is not needed.

BACT/ALERT 3D SelectLink:

The perfect option for routine microbial testing where exchange of basic data and results with the LIS is a necessity.

Accelerated by CLARION™

Publications

Weinstein MP, Mirrett S, Reimer LG, Wilson ML, Smith-Elekes S, Chuard CR, Joho KL, Reller LB. Controlled evaluation of BACT/ALERT standard aerobic and FAN® aerobic blood culture bottles for detection of bacteremia and fungemia. J Clin Microbiol. 1995;33(4):978-981.

Wilson ML, Weinstein MP, Mirrett S, Reimer LG, Feldman RJ, Chuard CR, Reller LB. Controlled evaluation of BACT/ALERT® standard anaerobic and FAN® anaerobic blood culture bottles for the detection of bacteremia and fungemia. J Clin Microbiol. 1995;33(9):2265-2270.

McDonald LC, Fune J, Gaido LB, Weinstein MP, Reimer LG, Flynn TM, Wilson ML, Mirrett S, Reller LB. Clinical importance of increased sensitivity of BACT/ALERT® FAN® aerobic and anaerobic blood culture bottles. J Clin Microbiol. 1996;34(9):2180-2184.

Mirrett S, Everts RJ, Reller LB. Controlled Comparison of Original Vented Aerobic FAN® Medium with New Nonvented BACT/ALERT® FA Medium for Culturing Blood. J Clin Microbiol.2001;39(6):2098-2101.

Mirrett S, Petti CA, Woods CW, Magadia R, Weinstein MP, Reller LB. Controlled Clinical Comparison of the BACT/ALERT® FN and the Standard Anaerobic SN Blood Culture Medium. J Clin Microbiol.2004;42(10):4581-4585.

Ziegler R, Johnscher I, Martus P, Lenhardt D, Just HM. Controlled clinical laboratory comparison of two supplemented aerobic and anaerobic media in automated blood culture systems to detect bloodstream infections. J Clin Microbiol. 1998; 36(3):657-661.

Pohlman JK, Kirkley BA, Easley KA, Basille BA, Washington JA. Controlled clinical evaluation of BACTEC Plus Aerobic/F and BACT/ALERT® aerobic FAN® bottles for detection of bloodstream infections. J Clin Microbiol. 1995;33(11):2856-2858.

Jorgensen JH, Mirrett S, McDonald LC, Murray PR, Weinstein MP, Fune J, Trippy CW, Masterson M, Reller LB. Controlled clinical laboratory comparison of BACTEC Plus Aerobic/F Resin medium with BACT/ALERT® Aerobic FAN® medium for detection of bacteremia and fungemia. J Clin Microbiol. 1997;35(1):53-58.

Altun O, Almuhayawi M, Ullberg M and Ozenci V, Clinical Evaluation of the FilmArray Blood Culture Identification Panel in Identification of Bacteria and Yeasts from Positive Blood Culture Bottles,J. Clin. Microbiol. 2013, 51(12):4130.

Amarsy-Guerle R, Mougari F, Jacquier H, Oliary J, Benmansour H, Riahi J, Bercot B, Raskine L and Cambau E. High medical impact of implementing the new polymeric bead-based BACT/ALERT®FA Plus and FN Plus blood culture bottles in standard care, Eur J Clin Microbiol Infect Dis. 2015 Feb. Doi: 10.1007/s10096-015-2319-8

Kirn TJ, Mirrett S, Reller LB, Weinstein MP, Controlled Clinical Comparison of BACT/ALERT FA Plus and FN Plus Blood Culture Media with BACT/ALERT FA and FN Blood Culture Media, J. Clin. Microbiol. doi:10.1128/JCM.03063-13.

Lee DH, Kim SC, Bae IG, Kim S, Clinical Evaluation of BACT/Alert FA Plus and FN Plus Bottles Compared with Standard Bottles, J. Clin. Microbiol. 2013, 51(12):4150.

Mitteregger D, Barousch W, Nehr M, Kundi M, Zeitlinger M , Makristathis A and Hirschl AM,Neutralization of Antimicrobial Substances in New BACT/Alert FA and FN Plus Blood Culture Bottles, J. Clin. Microbiol. 2013, 51(5):1534.

Doern C, Mirrett S, Halstead D, Abid J, Okada P and Reller B. Controlled Clinical Comparison of New Pediatric Medium with Adsorbent Polymeric Beads (PF Plus) versus Charcoal-Containing PF Medium in the BACT/Alert Blood Culture System. J. Clin. Microbiol. 2014 52(6): 1898-1900.

Fiori B, D'Inzeo T, Di Florio V, De Maio F, De Angelis G, Giaquinto A, Campana L, Tanzarella E, Tumbarello M, Antonelli M, Sanguinetti M, Spanu T. Performance of Two Resin-Containing Blood Culture Media in Detection of Bloodstream Infections and in Direct Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry (MALDI-TOF MS) Broth Assays for Isolate Identification: Clinical Comparison of the BACT/Alert Plus and Bactec Plus Systems. J. Clin. Microbiol. 2014 52(10): 3558-3567

Mirret S, Reller LB, Petti CA, Woods CW, Vazirani B, Sivadas R, and Weinstein MP. Controlled Clinical Comparison of BACT/ALERT® Standard Aerobic Medium with BACTEC Standard Aerobic Medium for Culturing Blood. J. Clin Microbiol. 2003; 41(6):2391-2394.

Bernard D, Verschraegen G, Claeys G, Lauwers S, Rosseel P. Bilophila wadsworthia bacteremia in a patient with gangrenous appendicitis. Clin Infect Dis. June 1994;18:1023-1024.

Bourbeau P, Riley J, Heiter BJ, Master R, Young C, Pierson C. Use of the BACT/ALERT® blood culture system for culture of sterile body fluids other than blood. J Clin Microbiol.1998;36(11):3273-3277.

Alfa MJ, Degagne P, Olson N, Harding KM. Improved detection of bacterial growth in continuous ambulatory peritoneal dialysis effluent by use of BACT/ALERT® FAN® bottles. J Clin Microbiol.1997;35(4):862-866.

Snyder JW, Munier GK, Bostic GD, Bozigar PS, Hanna R. Evaluation of a Plastic Nonvented Aerobic Blood Culture bottle for Use with the BACT/ALERT® Microbial Detection System. J Clin Microbiol. 2002; 40(12): 4757-4759.

Petti, CA, Mirrett S, Woods CW, and Reller LB. Controlled Clinical Comparison of Plastic versus Glass Bottles of BACT/ALERT® PF Medium for Culturing Blood from Children. J Clin Microbiol. 2005; 43(1): 445–447

Petti CA, Mirrett S, Woods CW, Reller LB, Controlled clinical comparison of plastic and glass bottles of BACT/ALERT® FA medium for culturing organisms from blood of adult patients. J Clin Microbiol. 2005; 43(4), 1960-1962

Alpern E, Alessandrini E, Bell L, Shaw K, McGowan L. Occult bacteremia from a pediatric emergency department: current prevalence, time to detection, and outcome. Pediatrics.2000;106(3):505-511.

McGowan K, Foster J, Coffin S. Outpatient pediatric blood cultures: time to positivity. Pediatrics.2000;106(2):251-255.

Krishner KK, Gibb P, CorbettS, and Church DEIDRE. Comparison of the BACT/ALERT® PF Pediatric FAN® Blood Culture Bottle with the Standard Pediatric Blood Culture Bottle, the Pedi-BACT J Clin Microbiol. 2001;39(8): 2880-2883.

Welby-Sellenriek PL, Keller DS, Ferrett RJ, Storch GA. Comparison of the BACT/ALERT® FAN®aerobic and the Difco ESP 80A aerobic bottles for pediatric blood cultures. J Clin Microbiol.1997;35(5):1166-1171.

Doern G, Barton A, Rao S. Controlled comparative evaluation of BACT/ALERT® FAN® and ESP 80A aerobic media as means for detecting bacteremia and fungemia. J Clin Microbiol. 1998; 35(9):2686-2689.

Alcaide F, Benitez MA, Escriba JM, Martin R. Evaluation of the BACTEC MGIT™ 960 and the MB/BACT systems for recovery of mycobacteria from clinical specimens and for species identification by DNA AccuProbe. J Clin Microbiol. 2000;38(1):398-401.

Crump J, Tanner DC, Mirrett S, McKnight CM, Reller LB, Controlled Comparison of BACTEC 13A, Myco/F Lytic, BACT/ALERT® MB and Isolator 10 Systems for Detection of Mycobacteremia. J Clin Microbiol. 2003;41(5):1987-1990.

McDonald, L., Weinstein, M., Fune, J., Mirrett, S., Reimer, L., Reller, B., Controlled Comparison of BACT/ALERT® FAN® Aerobic Medium and Bactec Fungal Blood Culture Medium for Detection of Fungemia, J Clin Microbiol. 2001:39(2): 622–624.

Bourbeau P and Foltzer M. Routine Incubation of BACT/ALERT FA and FN Blood Culture Bottles for More than 3 Days May Not Be Necessary. J Clin Microbiol. 2005: 43(5): 2506-2509.

Seegmuller I, Eschenbach U, Kamereck K. Sensitivity of the BACT/ALERT® FA medium for detection of Pseudomonas aeruginosa in pre-incubated blood cultures and its temperature dependence. J Med Microbiol. (2004); 53. 869-874.

PRN 054364 Rev.01A

BACT/ALERT® 3D

Overview